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. 2018 Jun 21;115(1):168–178. doi: 10.1093/cvr/cvy157

Figure 6.

Figure 6

Hypoxia-inducible factor 1α (HIF1α) knockdown decreased the expression of vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2) proteins in endothelial cells. (A) expression of VEGF protein in endothelial cells (top: representative western blot bands of VEGF); (B) expression of VEGFR2 protein in endothelial cells (top: representative bands of western blot bands of VEGFR2). Endothelial cells were infected with lentiviral vectors containing HIF1α shRNA (shRNA) or scrambled HIF1α shRNA sequence (SCR). Data are presented as mean ± SEM. *P < 0.05 vs. control; †P < 0.05 vs. SCR analysed by Kruskal–Wallis test followed by Dunn’s test (n = 5).