Figure 1.

Hematological parameters of Hbb^th3/+mice with BM-specific deletion of Tfr2. The hematological parameters of mice were analyzed monthly from 9 to 22 weeks after transplantation with a thalassemic (Hbb^th3/+) or a Tfr2^−/−/Hbb^th3/+ (Tfr2^BMKO/Hbb^th3/+) BM. Mice were fed a standard diet. In the figure are graphed: (A) RBC; (B) Hb; (C) MCV; and (D) MCH. Mean values of 6 to 8 animals for genotype are graphed. The dotted red line indicates mean value in wt mice.⁴⁰ Error bars indicate SE. Asterisks refer to statistically significant differences between age-matched Hbb^th3/+ and Tfr2^BMKO/Hbb^th3/+ mice: *P < .05; **P < .01; ***P < .005.