Table 2.

Expression level of NF-κB target genes involved in ROS protection from RNAseq analysis of the spleen of Hbb^th3/+ and Tfr2^BMKO/Hbb^th3/+ mice

Gene name	Hbbth3/+	Tfr2BMKO/Hbbth3/+	P (DESeq2)*	padj (IHW)†
Sod2 (MnSOD)	41.02 ± 0.73	51.43 ± 3.26	.006551	.056003
Sod1 (CuZnSOD)	1205.18 ± 100.71	1617.59 ± 98.45	.005153	.045185
FtH1	5377.17 ± 414.93	6666.98 ± 593.60	.030397	.134317
Txn1	627.74 ± 18.86	735.73 ± 80.39	.054498	.195756
Txn2	74.12 ± 5.09	92.57 ± 3.54	.014006	.083579
GSTp1	124.66 ± 11.92	171.08 ± 17.92	.00604	.059385

Data are indicated as median of the TPM plus or minus standard error of the mean.

FtH1, ferritin heavy chain 1; GSTp1, glutathione S-transferase P1; IHW, independent hypothesis weighting; padj, adjusted P value; ROS, reactive oxygen species; Sod, superoxide dismutase; TPM, transcripts per kilobase million; Txn, thioredoxin.

^*The P value has been calculated using the DESeq2 algorithm.

^†The adjusted P value has been obtained using the IHW correction.