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. 2018 May 30;115(1):179–189. doi: 10.1093/cvr/cvy136

Figure 8.

Figure 8

Mice expressing scFV-E06 have reduced infarct size following myocardial IR. (A) Representative myocardial TTC staining of LDLR−/− (n = 15) and scFvE06/LDLR−/− (n = 14) groups 7 days after 60 min of ischaemia. White indicates infarct; red, viable myocardium; and non-blue, AAR. (B) There were no significant difference in AAR normalized by LV mass distal to the ligation for ischaemia (AAR/LV). Compared to controls, E06-scFv/Ldlr−/− mice had 65.9% smaller IA/AAR (P = 0.0023) (C) and 58.5% smaller IA/LV (P = 0.0025) ANOVA. TTC, 2, 3, 5-triphenyltetrazolium chloride; AAR, area at risk; LV, left ventricle; IA, infarct area.