Table 4.

Weight-bands for levofloxacin (100 mg and 250 mg tablets) and resulting drug exposures

Weight-bands (kg)		Tablets of levofloxacin 100 (n)	Tablets of levofloxacin 250 (n)	Range of resulting dosages (mg/kg)
				Levofloxacin 100		Levofloxacin 250
				Min	Max	Min	Max
3	4.9	0.5	0.25	10	17	13	21
5	6.9	1	0.5	14	20	18	25
7	9.9	1.5	0.75	15	21	19	27
10	11.9	2	1	17	20	21	25
12	15.9	2.5	1	16	21	16	21
16	19.9	3	1.5	15	19	19	23
20	24.9		1.5			15	19
25	29.9		2			17	20

Target dosage for levofloxacin is in the range of 15–20 mg/kg

Children in the placebo arm will receive the same number of tablets based on their weight-band