Table 8.
Two proportion z-test | |||||
---|---|---|---|---|---|
TCGA data set |
Superset Jaccard Indexa |
Gene set Jaccard Indexb |
Superset Proportionc |
Gene set Proportiond |
P-valuee |
BRCA | 0.344 | 0.124 | 11 / 24 | 31 / 197 | 0.0002 |
LUAD | 0.182 | 0.113 | 6 / 12 | 32 / 145 | 0.0150 |
SKCM | 0.179 | 0.069 | 5 / 19 | 17 / 139 | 0.0485 |
LGG | 0.483 | 0.475 | 29 / 45 | 299 / 481 | 0.3821 |
Supersets/gene sets with log-rank P-value < 0.05 were selected as prognostic significant sets. aJaccard index of significant supersets between training and test data. bJaccard index of significant gene sets between training and test data. cSuperset proportion: (# of overlapped significant supersets between training and test data) over (# of significant supersets in training data). dGene set proportion: (# of overlapped significant gene sets between training and test data) over (# of significant gene sets in training data). eThe P-value of z-test comparing superset and gene set proportions