Fig. 2.

The hierarchical clustering and involved biological processes analysis of differentially expressed proteins between the HIV/TM-coinfected-and HIV-mono-infected patient serum samples. a Volcano plot represented the protein abundance changes (b vs. a). A total of 123 dysregulated proteins with fold change ≥ ± 1.5 and p values < 0.05 were identified. b Hierarchical clustering of the 123 dysregulated proteins (B vs. A). c, d GO analysis of the upregulated proteins (c) and downregulated proteins (d) involved biological processes in the HIV/TM co-and HIV mono-infected patient serum samples (b vs. a). Only terms with p values less than 0.001 are shown