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. 2018 Dec 20;16:368. doi: 10.1186/s12967-018-1744-8

Table 4.

Association of the PCG-lncRNA signature with clinicopathological characteristics in postoperative GBM patients in TCGA dataset

Variables Training set P Test set P Entire TCGA set P
Low riska High riska Low riska High riska Low riska High riska
Age 0.76 1 0.93
 < 60 21 20 19 16 40 36
 ≥ 60 17 18 22 20 39 38
Sex 0.23 0.97 0.52
 Female 10 16 16 13 26 29
 Male 28 22 25 23 53 45
TMZ-chemotherapy 0.16 0.51 0.11
 No 4 10 6 9 10 19
 Yes 30 23 31 24 61 47
 Unknown 4 5 4 3 8 8
Radiotherapy 0.01 0.26 0.01
 No 1 7 5 8 6 15
 Yes 36 26 36 27 72 53
 Unknown 1 5 0 1 1 6
TMZ-chemoradiation 0.01 0.03 < 0.001
 No 14 27 17 25 31 52
 Yes 23 10 20 9 43 19
 Unknown 1 1 2 4 3 5
Subtype 0.8 0.34 0.47
 Classical 9 9 8 14 17 23
 Mesenchymal 13 10 15 11 28 21
 Neural 6 9 6 5 12 14
 Proneural 10 10 11 6 21 16

aLow risk ≤ median value of the PCG-lncRNA signature risk score, high risk > median of risk score in training group; The Chi-squared test; P value < 0.05 was considered significant; TMZ temozolomide