Table 4.
Variables | Training set | P | Test set | P | Entire TCGA set | P | |||
---|---|---|---|---|---|---|---|---|---|
Low riska | High riska | Low riska | High riska | Low riska | High riska | ||||
Age | 0.76 | 1 | 0.93 | ||||||
< 60 | 21 | 20 | 19 | 16 | 40 | 36 | |||
≥ 60 | 17 | 18 | 22 | 20 | 39 | 38 | |||
Sex | 0.23 | 0.97 | 0.52 | ||||||
Female | 10 | 16 | 16 | 13 | 26 | 29 | |||
Male | 28 | 22 | 25 | 23 | 53 | 45 | |||
TMZ-chemotherapy | 0.16 | 0.51 | 0.11 | ||||||
No | 4 | 10 | 6 | 9 | 10 | 19 | |||
Yes | 30 | 23 | 31 | 24 | 61 | 47 | |||
Unknown | 4 | 5 | 4 | 3 | 8 | 8 | |||
Radiotherapy | 0.01 | 0.26 | 0.01 | ||||||
No | 1 | 7 | 5 | 8 | 6 | 15 | |||
Yes | 36 | 26 | 36 | 27 | 72 | 53 | |||
Unknown | 1 | 5 | 0 | 1 | 1 | 6 | |||
TMZ-chemoradiation | 0.01 | 0.03 | < 0.001 | ||||||
No | 14 | 27 | 17 | 25 | 31 | 52 | |||
Yes | 23 | 10 | 20 | 9 | 43 | 19 | |||
Unknown | 1 | 1 | 2 | 4 | 3 | 5 | |||
Subtype | 0.8 | 0.34 | 0.47 | ||||||
Classical | 9 | 9 | 8 | 14 | 17 | 23 | |||
Mesenchymal | 13 | 10 | 15 | 11 | 28 | 21 | |||
Neural | 6 | 9 | 6 | 5 | 12 | 14 | |||
Proneural | 10 | 10 | 11 | 6 | 21 | 16 |
aLow risk ≤ median value of the PCG-lncRNA signature risk score, high risk > median of risk score in training group; The Chi-squared test; P value < 0.05 was considered significant; TMZ temozolomide