Table 3.
Anatomic sites of infection and the five most common antimicrobial drugs (ATC level 5) prescribed
| Anatomic sitesa | Top 5 antibiotic use (ATCa level 5) among paediatric patients | ||||
|---|---|---|---|---|---|
| 1st | 2nd | 3rd | 4th | 5th | |
| Resp (n = 196) |
Gentamicin (n = 35, 17.9%) | Cefuroxime (n = 34, 17.3%) | Ceftriaxone (n = 29, 14.8%) | Amox-clav (n = 18, 9.2%) | Cloxacillin (n = 12, 6.1%) |
| C penicillin | |||||
| SSTBJ (n = 131) | Metronidazole (n = 24,18.3%) | Cloxacillin (n = 23, 17.6%) | Clindamycin (n = 20, 15.3%) | Cefuroxime (n = 19, 14.5%) | Amox-clav (n = 17, 13.0%) |
| GIT (n = 88) | Metronidazole (n = 29, 32.9%) | Cefuroxime (n = 17,19.3%) | Ciprofloxacin (n = 13,14.8%) | Ceftriaxone (n = 11,12.5%) | Gentamicin (n = 7, 8.0%) |
| GUOB (n = 33) | Metronidazole (n = 8,24.2%) | Amox-clav (n = 7, 21.2%) | Cefuroxime (n = 5, 15.2%) | Ceftriaxone (n = 4, 12.1%) | Ciprofloxacin (n = 3, 9.1%) |
| CNS (n = 26) |
Amox-clava (n = 2, 7.7%) | Ceftriaxone (n = 11, 3.4%) | Cloxacillin (n = 5, 1.5%) | Metronidazole (n = 3,0.9%) | Gentamicin (n = 1, 0.3%) |
| Cefuroxime | Cefotaxime | ||||
| Meropenem | |||||
| UTI (n = 14) |
Cefuroxime (n = 5, 35.7%) | Ciprofloxacin (n = 3, 21.4%) | Other drugsb (n = 6, 43.8%) | – | – |
| Other sites (n = 15) |
Ceftriaxone (n = 4, 26.6%) | Amox-clav (n = 2, 13.1%) | Other drugsc (n = 4, 26.6%) | – | – |
| C penicillina | |||||
| UND (n = 328) | Gentamicin (n = 59,18.0%) | Ceftriaxone (n = 57, 17.4%) | Ampicillin (n = 45,13.7%) | Cloxacillin (n = 42,12.8%) | Amikacin (n = 25,7.6%) |
aResp respiratory tract, GIT Gastrointestinal tract, UTI Urinary tract infection, CNS Central nervous system, SSTBJ skin, soft tissue, bones and joints, GUOB Genitourinary and obstetrics; Other sites comprise cardiovascular system and Ear, nose and throat; UND Undefined, Amox-clav Amoxicillin-clavulanic acid, C pencillin Crystal penicillin, ATC Anatomical Therapeutic Chemical Classification System
bother drugs include crystal penicillin (n = 1), ceftriaxone (n = 1), gentamicin (n = 1), meropenem (n = 1), nitrofurantoin (n = 1), erythromycin (n = 1)
cothers include crystal penicillin (n = 1), ceftriaxone (n = 1), gentamicin (n = 1), meropenem (n = 1), nitrofurantoin (n = 1), erythromycin (n = 1)