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. 2018 Dec 21;19(Suppl 18):483. doi: 10.1186/s12859-018-2510-x

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — First PhysiCell-EMEWS test on cancer hypoxia: analytics. Live tumor cell count (top) and live cell fraction (bottom) after 48 h, as a function of oxygenation conditions (each curve is a different condition) and initial cell count (horizontal axis). For intermediate oxygenation conditions, increasing the initial cell count increases the final live cell count (top) but decreases the live cell fraction (bottom). Once oxygenation is high enough, any initial cell count yields nearly 100% live fraction at 48 h