Table 3.

The analysis of mean peptide intensity per gene symbol for Haptoglobin related protein by ANOVA with Tukey–Kramer multiple means comparison

Treatment_ID	Mean	SD	SE (mean)	data:n	Tukey
1	4.62	0.35	0.08	20	bc
2	4.63	0.91	0.30	9	abc
3	5.07	NA	NA	1	cd
4	5.03	0.19	0.11	3	cd
5	5.12	0.58	0.09	46	ad
6	4.46	0.17	0.05	14	c
7	4.97	0.07	0.03	6	cd
9	5.34	0.42	0.02	687	d
10	5.35	0.41	0.01	951	d
13	4.51	0.64	0.14	21	c
14	4.45	0.65	0.17	14	c
15	4.63	0.23	0.09	7	abc
16	4.45	0.18	0.06	8	bc
17	4.81	0.81	0.40	4	cd
18	4.25	0.63	0.45	2	abc
19	4.62	0.86	0.35	6	abc
20	4.30	0.58	0.20	8	c
21	4.45	0.63	0.21	9	c
22	4.43	0.49	0.22	5	abc
23	5.30	0.00	0.00	2	cd
24	5.31	1.01	0.45	5	bd
25	5.38	1.02	0.51	4	bd

Response: log₁₀_Intensity

Sum Sq Df F value Pr(>F)

Peptide_Sequence 102.746 58 13.867 < 2.2e−16 ***

Treatment_ID 29.231 18 12.712 < 2.2e−16 ***

Peptide_Sequence:Treatment_ID  21.039   37   4.451 < 2.2e−16 ***

Residuals 219.478 1718

Treatment ID numbers: 1, Alzheimer normal; 2, Alzheimer normal control STYP; 3, Alzheimer’s dementia; 4, Alzheimer’s dementia STYP; 5, Cancer breast; 6, Cancer breast STYP; 7, Cancer control; 8, Cancer control STYP; 9, Cancer ovarian; 10, Cancer ovarian STYP; 11, Ice Cold; 12, Ice Cold STYP; 13, Heart attack Arterial; 14, Heart attack Arterial STYP; 15, Heart attack normal control; 16, Heart attack normal Control STYP; 17, Heart attack; 18, Heart attack STYP; 19, Multiple Sclerosis normal control; 20, Multiple Sclerosis normal control STYP; 21, Multiple Sclerosis; 22, Multiple Sclerosis STYP; 23, Sepsis; 24, Sepsis STYP; 25, Sepsis normal control; 26, Sepsis normal control STYP. STYP: serine, threonine, tyrosine phosphorylation. Note that many proteins were not detected in the ice cold plasma