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. 2018 Dec 20;37:320. doi: 10.1186/s13046-018-0993-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — The miR-133a-3p-autophagy-glutaminolysis pathway distributes to a favorable environment for GC cells. (a). It was confirmed that the autophagy and glutaminolysis inhibition by siRNA and drug could further decrease survival abilities of LV-miR-133a-3p GC cells by clonogenic survival assay. (b). It was confirmed as well that the autophagy and glutaminolysis inhibition by siRNA and drug could further decrease mitochondrial respiration of LV-miR-133a-3p GC cells by oxygen consumption rate (OCR) assay. All data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001