Table 2.
Recommended regimens for treatment with standard anticoagulation in children [2]
| Anticoagulant drug | Age or body weight | Initial dosage | Target |
|---|---|---|---|
| Warfarin | INR 2.0–3.0 | ||
| Acenocoumarol | INR 2.0–3.0 | ||
| Phenprocoumon | INR 2.0–3.0 | ||
| Unfractionated heparin | aPTT times 1.5–2.5 | ||
| Enoxaparin | < 2 months | 1.5 mg/kg bid | |
| > 2 months | 1 mg/kg bid | ||
| Tinzaparin | < 2 months | 275 U/kg od | |
| 2–12 months | 250 U/kg od | ||
| 1–5 years | 240 U/kg od | ||
| 5–10 years | 200 U/kg od | ||
| > 10 years | 175 U/kg od | ||
| Dalteparin | 129 ± 43 U/kg od | ||
| Reviparin | < 5 kg | 150 U/kg bid | |
| > 5 kg | 100 U/kg bid | ||
| Fondaparinux | 0.1 mg/kg od |
aPPT activated partial thromboplastin time; bid twice-daily; INR international normalized ratio; od once-daily; U unit