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. 2018 Oct 23;68(1):141–155. doi: 10.2337/db18-0232

Figure 4.

Figure 4

Nrf2 activation restores multipotency in dBMSCs. A: Stained db/db and siKeap1-dBMSCs at P3 and 14 days in differentiation media as indicated. Panel iii magnification is 20×. B and C: Relative expression of adipogenic genes. D–F: Relative expression of osteogenic genes. G and H: Relative expression of chondrogenic genes. I: Transwell migration assay using WT or dBMSCs as indicated. J: Relative expression of cell cycle regulators. K: Proliferation in cells using MTT assay. Data represented as mean ± SD; n ≥ 3. *P < 0.05; **P < 0.01.