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Silencing of Sirt1 mitigated the positive effect of aerobic exercise training on diabetes-associated lower expression of Sirt1 and PGC1α in diabetic kidneys. Western blot analysis was used to measure expression of Sirt1 (A) and PGC1α (B) in protein level. Bar charts represent means ±SEM (n=7). ** P<0.01 vs. Sed-Control; ## P<0.01 vs. Sed-Diabetes; $$ P<0.01 vs. Aex-Diabetes.
