Table 4.

Multiple linear regression models to determine the relationships between demographic indices, currently-recognized monocyte subsets, and renal function in study subjects with no CKD + CKD 1-5.

Model	Cohort	Number	Response variable	Explanatory variable	Coefficient	95% CI	†P
2a	No CKD + CKD 1-5	169	eGFR	Constant	100.54	86.88, 114.2	< 0.001
				Age (years)	−25.39	−31.38, −19.4	< 0.001
				Gender (M)	5.11	−1.97, 12.18	0.16
				#Classical	−4.18	−8.34, −0.02	0.049
				#Intermediate	−5.36	−9.35, −1.37	0.009
				#Non-classical	3.31	−1.07, 7.69	0.14
2b (age adjusted)	No CKD + CKD 1-5	169	eGFR	Constant	105.38	92.43, 118.32	< 0.001
				Age (years)	−25.06	−31.07, −19.08	< 0.001
				#Classical	−3.98	−8.15, 0.19	0.06
				#Intermediate	−4.26	−8.11, −0.41	0.03

^†Statistical test = a) Multiple linear Regression Model, b) Multiple linear Regression Model with age correction.

^#Represented as cells/mL. Cell types for which significant results were observed are bolded for emphasis.