Table 2.

IOP and glaucoma progression on VF

	HRa	95% CI	P-value
Univariate analysis
Mean
Short-term IOP	1.09	0.96–1.24	0.19
Long-term IOP	1.04	0.93–1.16	0.46
SD
Short-term IOP	1.15	1.07–1.23	<0.0001
Long-term IOP	0.98	0.70–1.35	0.88
Max
Short-term IOP	1.05	1.02–1.07	<0.0001
Long-term IOP	1.04	1.02–1.07	0.001
Multivariate analysisb
Mean
Short-term IOP	1.35	0.65–2.82	0.42
Long-term IOP	0.75	0.27–2.09	0.59
SD
Short-term IOP	1.37	1.18–1.59	<0.0001
Long-term IOP	0.76	0.49–1.18	0.21
Max
Short-term IOP	1.06	1.03–1.10	0.0005
Long-term IOP	1.27	0.98–1.64	0.07

Notes:

^aUnivariate and multivariate Cox regression analysis of glaucoma progression on VF. Eighty-six eyes of 44 patients with primary open-angle, pseudoexfoliation and normal tension glaucoma were included; patients with pigmentary glaucoma and other glaucoma did not progress.

^bThree multivariable models were fitted, one for each of mean, SD, and max. Each model included gender, age, and one short-term and long-term IOP parameter. Short-term IOP parameters were derived from the latest IOP profile. Long-term parameters were derived from means of short-term IOP profiles up to the latest visit. Bold text indicates statistical significant results.

Abbreviations: IOP, intraocular pressure; max, maximum; SD, standard deviation; VF, visual field.