Table 2.

Results of the clinicopathological parameters for gastric cancer with lymph node involvement by multivariate logistic analyses

	Lymph node involvement
	Total		Epithelial cell-negative group
Variables	OR (95% CI)	P-value	OR (95% CI)	P-value
Periostin expression in epithelial cell or expression level in stroma (positive vs negative or high level vs low level)	0.494 (0.268–0.909)	<0.001	0.935 (0.522–1.676)	0.028
Diameter (cm; ≥4 vs <4)	2.375 (1.393–4.050)	<0.001	2.925 (1.611–5.310)	<0.001
Lauren type (diffuse type/intestinal type)	1.578 (0.907–2.744)	<0.001	1.470 (0.804–2.687)	<0.001
Serum CEA (ng/mL; ≥5 vs <5)	3.549 (1.534–8.211)	<0.001	3.416 (1.274–9.156)	<0.001
Serum CA19-9 (U/mL; ≥37 vs <37)	1.737 (0.819–3.685)	0.003	1.387 (0.606–3.172)	0.031
Serum CA72-4 (U/mL; ≥6.9 vs <6.9)	1.199 (0.622–2.313)	0.005	1.252 (0.601–2.608)	0.031
Depth of invasion (T3+T4 vs T0+T1+T2)	4.387 (2.545–7.562)	<0.001	3.369 (1.864–6.088)	<0.001
Differentiation status (poorly vs well+moderately)	1.897 (1.066–3.377)	<0.001	1.911 (1.012–3.607)	<0.001

Abbreviations: CA19-9, carbohydrate antigen 19-9; CA72-4, carbohydrate antigen 72-4; CEA, carcinoembryonic antigen.