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. 2018 Dec 18;14:17–32. doi: 10.2147/IJN.S175340

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Apoptosis of HGC27 cells after exposure to blank PEG-PCL, PEG-PCL-IgG, PEG-PCL-mAb, DOC, DOC-PEG-PCL-IgG, and DOC-PEG-PCL-mAb NPs.

Notes: (A) Scatter plot indicating the cell populations in apoptotic and necrotic quadrants with the percentage of cancer cell death posttreatment of different NPs. (B) Western blot data of apoptosis showing the expression of proapoptotic and antiapoptotic proteins. Data were presented as the mean±SD of three independent experiments. ***P<0.005, **P<0.01, and *P<0.05 were considered significant.

Abbreviations: Bcl-2, B-cell lymphoma 2; DOC, docetaxel; IgG, immunoglobulin G; mAb, monoclonal antibody; NP, nanoparticle; PEG-PCL, poly (ethylene glycol)-poly (ε-caprolactone).