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. 2018 Dec 18;14:17–32. doi: 10.2147/IJN.S175340

Figure 7.

Figure 7

DOC-PEG-PCL-mAb NPs enhance G2/M arrest.

Notes: (A) The influence of cell cycle was analyzed using PI/RNase buffer. Compared with control group, DOC-PEG-PCL-mAb NPs significantly induced cell cycle arrest at the G2/M phase. (B) Cyclin A and B protein accumulated in the DOC-PEG-PCL-mAb NPs-treated group. ***P<0.005 and **P<0.01 were considered significant.

Abbreviations: DOC, docetaxel; IgG, immunoglobulin G; mAb, monoclonal antibody; NP, nanoparticle; PE-A, phycoerythrin-A; PEG-PCL, poly (ethylene glycol)-poly (ε-caprolactone); PI, propidium iodide.