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. 2018 Dec 18;14:17–32. doi: 10.2147/IJN.S175340

Table 1.

PD-L1 mAb content of the PEG-PCL-mAb NPs of various NPs/mAb ratios used in the process

Ratio of PEG-PCL to PD-L1 mAb (% w/w) PD-L1 mAb content (% w/w)
10 4.2±0.23
20 9.7±0.55
30 17.6±1.21
40 22.5±0.83
50 23.1±1.43
60 22.8±1.62

Note: 40% weight ratio (w/w) of PEG-PCL/PD-L1 mAb was the best choice to synthesize PEG-PCL-mAb copolymers.

Abbreviations: mAb, monoclonal antibody; NP, nanoparticle; PD-L1, programmed death-ligand 1; PEG-PCL, poly (ethylene glycol)-poly (ε-caprolactone).