Table 3:
Evaluation of resistance mutations in acetylcholine esterase and their status in ATUMI
| Torpedo Ace position | ATUMI_Ace1 position | Resistance mutations | ATUMI_Ace1 state |
|---|---|---|---|
| 119 | 189 | G247S, G119D | G |
| 128 | 198 | D237E | D |
| 201 | 270 | A302S | A |
| 227 | 296 | G265A, G262A | G |
| 290 | 358 | F290V | F |
| 331 | 399 | S431F, F445W, F439C | F |
| Torpedo Ace position | ATUMI_Ace2 position | Resistance mutations | ATUMI_Ace2 state |
| 78 | 114 | F139L, F115S | F |
| 82 | 118 | E81K | E |
| 129 | 177 | I161V/T | I |
| 151 | 198 | V180L | I |
| 227 | 280 | G265A, G262A/V | G |
| 238 | 290 | S291G | T |
| 290 | 358 | F330Y, F237Y | F |
| 328 | 383 | G365A, G368A | G |
| 396 | 452 | G488S | G |
Torpedo Ace position number and the resistance mutations are described in [46]