Fig 5. Effect of rTWEAK on ICAM1, MMP1, MMP2, MMP7, MMP9, and IL1B mRNA levels in GO cells.

(A, B) GO orbital fibroblasts (n = 3) were cultured and treated with rTWEAK (10 and 100 ng/ml) for 6 h (A) and 24 h (B). ICAM1, MMP1, MMP2, MMP7, MMP7, MMP9, and IL1B mRNA levels were evaluated by real-time PCR. Data in columns represent the mean fold difference in relative mRNA level ± standard deviation from triplicate measurements. *P < 0.05 vs. untreated control cells.