Fig. 1.

Geographic location of Kyrgyz population (box) relative to other major populations from the 1000 Genome Project used in the Admixture analysis of current study (a). YRI Yoruba in Ibadan, Nigeria, CEU Utah Residents with Northern and Western European Ancestry, JPT Japanese in Tokyo, Japan, CHB Han Chinese in Beijing, China, SAS (PJL), Punjabi from Lahore, Pakistan. b Topography of Kyrgyz republic with > 90% of the area at altitude > 3000 m above sea level. c Mean pulmonary artery pressure (mPAP) in healthy Kyrgyz highlanders (No-HAPH) is significantly lower than the age-matched HAPH patients. Error bar represents ± standard error