Table 2.
Part 1 | Part 3 | ||||||
---|---|---|---|---|---|---|---|
Cohort | All | 1 | 2 | 3 | 4 & 6 | 5 | N/A |
Food state | Both | Fasted | Fasted | Fasted | Fasted | Fed | Fed |
Dose | Placebo | 0.6 mg | 2.0 mg | 6.0 mg | 18.0 mg | 6.0 mg | 6.0 mg |
Male, n (%) | 7 (100) | 3 (100) | 3 (100) | 3 (100) | 6 (100) | 3 (100) | 8 (100) |
Race, n (%) | |||||||
White | 3 (43) | 3 (100) | 2 (67) | 2 (67) | 6 (100) | 3 (100) | 5 (63) |
Black | 2 (29) | – | – | 1 (33) | – | – | 1 (13) |
Asian | 2 (29) | – | 1 (33) | – | – | – | 1 (13) |
Multiple | – | – | – | – | – | – | 1 (13) |
Age, mean years (SD) | 27.0 (6.9) | 23.7 (5.1) | 25.0 (7.0) | 23.0 (3.0) | 22.8 (2.1) | 32.0 (10.1) | 29.4 (8.0) |
Weight, mean kg (SD) | 80.6 (8.4) | 84.2 (5.9) | 68.5 (17.5) | 85.0 (6.5) | 75.3 (8.5) | 80.7 (14.6) | 80.8 (11.5) |
BMI mean kg m –2 (SD) | 24.3 (3.5) | 24.5 (1.6) | 21.1 (3.4) | 26.2 (1.6) | 23.2 (1.4) | 24.5 (2.9) | 25.0 (3.5) |
BMI, body mass index; N/A, not applicable; SD, standard deviation