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. 2018 Dec 21;9:5440. doi: 10.1038/s41467-018-07772-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Virus dissemination in mice infected with ECTV mutants. Five Balb/c mice per condition were s.c. inoculated in the footpad with 10³ pfu of the indicated ECTV recombinants and virus titres in footpad, spleen and liver were determined by plaque assay at 5 and 7 dpi. Independent virus titres from each infected animal and the mean value are shown. Data below the detection limit of the assay (10² pfu/mg) are not depicted. Statistical significance indicated after Mann–Whitney test, assuming 0 value for undetectable viral loads