Table 3.
Summary of adjudicated causes of treatment-emergent death.
| Adjudicated causes of death,an (%) | Deaths (n = 33) |
|---|---|
| Bleeding | 1 (3.0) |
| Extracranial haemorrhage | 0 |
| Intracranial bleeding | 1 (3.0) |
| Cancer | 3 (9.1) |
| Cardiovascular | 12 (36.4) |
| Cardiac decompensation, heart failure | 7 (21.2) |
| Dysrhythmia | 1 (3.0) |
| Myocardial infarction | 2 (6.1) |
| Non-haemorrhagic stroke | 1 (3.0) |
| Sudden or unwitnessed death | 2 (6.1) |
| Venous thromboembolism | 0 |
| Other vascular event | 1 (3.0) |
| Systemic embolism | 0 |
| Infectious disease | 7 (21.2) |
| Other | 6 (18.2) |
| Unexplained | 7 (21.2) |
a
Multiple reasons were recorded for the cause of adjudicated treatment-emergent death of some patients.