Table 2.
Studies | LncRNAs | Country | Sample Type | Case number (High/Low) | Method | Cut-off | Tumor stage | outcome | HR availability | NOS |
---|---|---|---|---|---|---|---|---|---|---|
Jiang 2017 | DANCR | China | Tissue | 34(17/17) | qRT-PCR | NA | NA | OS,DFS | Directly | 7 |
Wen 2017 | UCA1 | China | Tissue | 151 (75/76) | qRT-PCR | NA | IIA-III | OS,DFS | Directly | 7 |
Cai 2017 | HNF1A-AS1 | China | Tissue | 72 (36/36) | qRT-PCR | median | IIA-III | OS | Directly | 6 |
O'Leary 2017 | PARTICLE | Germany | Tissue | 40 (23/17) | qRT-PCR | NA | NA | OS,MFS | Indirectly | 7 |
Huo 2017 | MALAT1 | China | serum | 46 (18/26) | qRT-PCR | median | I-IV | OS,PFS | Indirectly | 6 |
Li 2017 | XIST | China | Tissue | 145 (75/70) | qRT-PCR | NA | I-IV | OS | Directly | 7 |
Wang 2017 | SOX2-OT | China | Tissue | 138 (69/69) | qRT-PCR | median | I-III | OS | Directly | 7 |
Zhou 2016 | CCAL | China | Tissue | 46 (23/23) | qRT-PCR | median | I-IV | OS | Directly | 7 |
Peng 2016 | BANCR | China | Tissue | 84 (42/42) | qRT-PCR | median | IIA-III | OS | Directly | 7 |
Ju 2016 | BCAR4 | China | Tissue | 168 (87/81) | qRT-PCR | median | IIA-III | OS | Directly | 7 |
Chen 2016 | BCAR4 | China | Tissue | 60 (30/30) | qRT-PCR | median | I-III | OS,RFS | Directly | 7 |
Ma 2016 | TUG1 | China | Tissue | 76 (41/35) | qRT-PCR | fold-change | I-III | OS,PFS | Directly | 8 |
Gao 2016 | MALAT1 | China | Tissue | 162 (80/82) | qRT-PCR | median | IIA-III | OS | Directly | 7 |
Cong 2016 | TUSC7 | China | Tissue | 82 (13/69) | qRT-PCR | fold-change | early-advanced | OS | Directly | 7 |
Uzan 2016 | HULC | Brazil | Tissue | 33 (12/21) | qRT-PCR | ROC | NA | OS,EFS | Indirectly | 8 |
Xia 2016 | 91H | China | serum | 67 (34/33) | qRT-PCR | median | I-III | OS | Directly | 8 |
Li 2016 | UCA1 | China | Tissue | 135 (68/67) | qRT-PCR | median | I-III | OS | Directly | 7 |
Tian 2015 | MEG3 | China | Tissue | 64 (32/32) | qRT-PCR | median | I-III | OS | Directly | 7 |
Li 2015 | HOTTIP | China | Tissue | 68 (34/34) | qRT-PCR | median | IIA-III | OS | Directly | 7 |
Sun 2015 | HULC | China | Tissue | 78 (39/39) | qRT-PCR | median | IIA-III | OS | Directly | 7 |
Notes: LncRNA, long non-coding RNA; qRT-PCR, quantities reverse transcription polymerase chain reaction; OS, overall survival; DFS, disease free survival; MFS, metastasis free survival; PFS, progression free survival; RFS, recurrence free survival; EFS, event free survival; HR, hazard ratio; NA, not available.