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Brushfield spots and Wölfflin nodules based on white versus near-infrared light.
| Iris color | Down syndrome | Control | p-value | ||
|---|---|---|---|---|---|
| White light | Near-infrared light | White light | Near-infrared light | ||
| Blue | 7 | 7 | 3 | 3 | |
| Hazel | 2 | 4 | 1 | 1 | |
| Brown | 0 | 18 | 1 | 4 | |
| All | 9 | 29 | 5 | 8 | <0.001* |
*p-value for both all detected Brushfield spots in Down syndrome versus Wölfflin nodules in controls and combined white versus near-infrared based light detection of iris spots and nodules.
