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Crystal structure of apo Alkbh5 (PDB: 4NJ4 (21)) showing the localization of the five cysteine residues (yellow sticks). α-helices are colored pink. β-strands are colored light blue. Missing residues in the x-ray structure (Leu145–Gly149) are indicated by a black curve. αKG is modeled in the protein active site and shown as green spheres. To see this figure in color, go online.
