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Box-plots of total scores for each molecular subgroup in the SHH-specific nomogram. Note the significant difference in the mean scores for SHH-pathway medulloblastoma versus other subgroups in training cohort (A) as well as validation cohort (B). Receiver operating characteristic (ROC) curves derived using SHH-specific nomograms demonstrate excellent accuracy of predicting SHH-pathway medulloblastoma in both the training cohort (C) and the validation cohort (D).
