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. 2018 Dec 9;8(12):e023651. doi: 10.1136/bmjopen-2018-023651

Table 3B.

GRADE system for rating strength of recommendations

Strength Definition
Strong When desirable effects of intervention clearly outweigh the undesirable effects or clearly do not.
Weak When the trade-offs are less certain—either because of low quality evidence or because evidence suggests desirable and undesirable effects are closely balanced.