Table 2.
Correlation of the expression of the two candidate miRNA and clinical features of SLE
Clinical characteristics | N | NovelmiRNA-25 | P | all-hsa-miR-1273h-5p | P |
---|---|---|---|---|---|
Leukocyte | |||||
< 3.5 | 2 | 0.39 ± 0.12 | 0.045 | 1.50 ± 0.67 | 0.452 |
3.5–9.5 | 16 | 5.80 ± 5.38 | 2.78 ± 2.00 | ||
> 9.5 | 3 | 0.64 ± 0.25 | 1.89 ± 1.02 | ||
Neutrophil | |||||
1.8–6.3 | 15 | 6.06 ± 5.48 | 0.002 | 2.91 ± 2.01 | 0.271 |
> 6.3 | 4 | 0.78 ± 0.34 | 1.72 ± 0.90 | ||
Albumin | |||||
< 40 | 14 | 4.89 ± 4.85 | 0.034 | 2.98 ± 1.98 | 0.748 |
40–55 | 1 | 16.81 | 3.65 | ||
C3 | |||||
< 0.79 | 15 | 5.67 ± 5.74 | 0.019 | 2.86 ± 2.04 | 0.173 |
0.79–1.52 | 7 | 1.55 ± 1.61 | 1.73 ± 0.72 | ||
C4 | |||||
< 0.16 | 17 | 4.68 ± 5.76 | 0.524 | 1.75 (1.15, 2.57) | 0.031 |
0.16–0.38 | 4 | 2.74 ± 2.12 | 3.91 (2.45, 6.17) | ||
Lupus anticoagulant | |||||
0.75–1.25 | 10 | 3.65 ± 5.57 | 0.561 | 2.11 ± 1.24 | 0.034 |
> 1.25 | 3 | 5.62 ± 4.57 | 4.58 ± 2.50 | ||
24 h urine protein | |||||
< 0.5 | 3 | 8.65 ± 8.17 | 0.074 | 4.36 ± 2.80 | 0.073 |
> 0.5 | 9 | 2.80 ± 2.73 | 2.11 ± 1.25 | ||
Alanine aminotransferase | |||||
7–40 | 14 | 5.36 ± 5.96 | 0.984 | 2.79 ± 1.98 | 0.61 |
> 40 | 2 | 5.45 ± 0.03 | 3.57 ± 1.96 | ||
Anti-ds-DNA antibody | |||||
Positive | 12 | 1.99 (0.53, 6.59) | 0.75 | 1.64 (1.07, 4.62) | 0.553 |
Negative | 6 | 2.10 (0.73, 11.75) | 1.64 (1.07, 4.62) |
C3/C4 complement 3/complement 4