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. 2018 Dec 19;12:75–85. doi: 10.2147/OTT.S192809

Figure 1.

Figure 1

LINC01296 was upregulated in bladder cancer and the expression level of LINC01296 was correlated with clinicopathological features of bladder cancer patients.

Notes: (A) Comparison of relative expressions of LINC01296 in cancer and normal tissues using the GEPIA database. (B) Comparison of relative expressions of LINC01296 in bladder cancer and adjacent normal tissues using the GEPIA database. (C) A microarray containing 37,000 lncRNA and 34,000 mRNA probes was used to screen differentially expressed lncRNAs in four pairs of bladder cancer patients. (D) Comparison of relative expressions of LINC01296 in 54 bladder cancer tissues and 24 normal bladder tissues using qRT-PCR. (E) Two groups were set up according to the mean expression of LINC01296 in tumor tissues. (F) The LINC01296 expression was significantly higher in patients with a higher tumor stage, lymph node metastasis and a higher pathologic grade. *P<0.05.

Abbreviations: BLCA, bladder urothelial carcinoma; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GEPIA, Gene Expression Profiling Interactive Analysis; lncRNA, long noncoding RNA; mRNA, messenger RNA; qRT-PCR, quantitative real-time polymerase chain reaction.