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. 2018 Nov 19;160(1):68–80. doi: 10.1210/en.2018-00850

Table 2.

Serum Measurements in AdGHRKO and Control Male and Female Mice

Male
Female
Control AdGHRKO P Value Control AdGHRKO P Value
NEFA 0.81 ± 0.06 0.78 ± 0.04 0.747 0.78 ± 0.05 0.79 ± 0.04 0.846
Leptin 6267 ± 1456 6845 ± 1538 0.789 2309 ± 310 2890 ± 690 0.417
Resistin 11,341 ± 1174 6391 ± 418 0.002a 15,149 ± 1752 8907 ± 911 0.014b
Adiponectin 21,530 ± 1216 14,150 ± 1544 0.001a 34,403 ± 1647 24,801 ± 2317 0.005a
MCP1 192 ± 64 122 ± 31 0.366 194 ± 43 106 ± 54 0.215
TNFa 56 ± 21 26 ± 10 0.241 45 ± 15 25 ± 17 0.385
IL-6 125 ± 28 102 ± 16 0.493 111 ± 14 87 ± 43 0.562
FGF21 71 ± 26 29 ± 11 0.154 61 ± 18 41 ± 10 0.390
FSTL1 68 ± 0 191 ± 78 0.130 143 ± 56 96 ± 19 0.494
Myostatin 297 ± 152 83 ± 34 0.186 160 ± 140 15 ± 1 0.392
OSTCRN 42 ± 5 31 ± 4 0.100 54 ± 4 27 ± 3 6 × 10−5c
SPARC 19,240 ± 1997 17,970 ± 1748 0.639 17,493 ± 1056 20,918 ± 1999 0.130

Values are represented in pg/mL (or mmol/L for NEFA) as mean ± SEM (n = 6 to 11 per group). Measurements made at 6 mo of age.

Abbreviations: FGF21, fibroblast growth factor 21; FSTL1, follistatin-related protein 1; MCP1, monocyte chemoattractant protein 1; OSTCRN, osteocrin/musclin; SPARC, osteonectin; TNFa, TNF-α.

a

P < 0.01.

b

P < 0.05.

c

P < 0.001.