Table 1.
Patients’ characteristics
| Characteristic | Patients with DTC and CLT n = 331 |
Patients with DTC and without CLT n = 576 |
P value | OR (Odds ratio) with 95% CI (confidence interval) |
|---|---|---|---|---|
| Female/Male, n (%) | 312/19 (94/6) | 489/87 (85/15) | < 0.0001 | 2.92 (1.74–4.90) |
| Median age at diagnosis, years (range) | 45 (18–79) | 50 (18–84) | < 0.0001 | – |
| Multifocality, n (%) | 68 (20.5) | 89 (15.5) | 0.0557 | 1.41 (1.00–2.01) |
| Capsule invasion, n (%) | 66 (19.9) | 83 (14.4) | 0.033 | 1.48 (1.04–2.11) |
| Extracapsular invasion, n (%) | 55 (16.6) | 143 (24.8) | 0.004 | 0.60 (0.43–0.85) |
| Nodal (N) involvement, n (%) | 32 (9.7) | 81 (14.1) | 0.048 | 0.65 (0.42–0.99) |
| Mean tumour size, mm (range) | 15.7 (1–250) | 12.1 (1–95) | 0.618 | – |
| Tumour diameter ≤ 10 mm, n (%) | 180 (54.4) | 305 (53.0) | 0.285 | 1.06 (0.81–1.39) |
| Papillary thyroid carcinoma, n (%) | 307 (92.7) | 530 (92.0) | 0.796 | 1.11 (0.66–1.85) |
| Classical, n (%) | 233 (70.4) | 414 (71.9) | 0.703 | 0.93 (0.69–1.25) |
| Follicular, n (%) | 50 (15.1) | 80 (13.9) | 0.694 | 1.10 (0.75–1.62) |
| Classical/follicular, n (%) | 11 (3.3) | 19 (3.3) | 1.000 | 1.01 (0.47–2.14) |
| Oxyphilic, n (%) | 9 (2.7) | 15 (2.6) | 1.000 | 1.05 (0.45–2.42) |
| Follicular/oxyphilic, n (%) | 4 (1.2) | 2 (0.3) | 0.199 | 3.51 (0.64–19.27) |
| Follicular thyroid carcinoma, n (%) | 24 (7.3) | 46 (8.0) | 0.796 | 0.90 (0.54–1.50) |
| Classical, n (%) | 16 (4.9) | 34 (5.9) | 0.583 | 0.71 (0.24–2.07) |
| Oncocytic (Hürthle cell) variant, n (%) | 8 (2.4) | 12 (2.1) |
Italics represents statistically significant values