Table 2.
Patients’ and tumours’ characterization due to the type of thyroid inflammation
| Characteristic | Focal lymphocytic thyroiditis (FLT) n = 37 |
Single lymphoid follicles without thyroid destruction (SLF) n = 69 |
Focal lymphocytic thyroiditis and SLF n = 18 |
Hashimoto’s thyroiditis n = 207 |
|---|---|---|---|---|
| Female/male, n (%) | 35/2 (95/5) | 65/4 (92/6) | 18/0 (100/0) | 194/13 (94/6) |
| Median age at diagnosis, years (range) | 50 (21–79) | 43 (18–72) | 41 (27–62) | 45 (18–79) |
| Multifocality, n (%) | 11 (29.7)a,c | 8 (11.6)a,b | 6 (33.3)a,c | 43 (20.8)a,b,c |
| Capsule invasion, n (%) | 9 (24.3)a,b | 21 (30.4)b | 2 (11.1)a,b | 34 (16.4)a |
| Extracapsular invasion, n (%) | 6 (16.2)a,c | 16 (23.2)b | 3 (16.7)a,c | 29 (14.0)a,c |
| Mean tumour size, mm (range) | 26.7 (2–250) | 9.2 (1–120) | 17.9 (1–90) | 8.2 (1–150) |
| Tumour diameter ≤ 10 mm, n (%) | 22 (59.5) | 36 (52.2) | 10 (55.6) | 112 (54.1) |
| Nodal (N) involvement, n (%) | 7 (18.9)a | 9 (13.0)a | 1 (5.6)b | 15 (7.2)b |
| Papillary thyroid carcinoma, n (%) | 36 (97.3) | 64 (92.8) | 17 (94.4) | 190 (91.8) |
| Classical, n (%) | 29 (78.4) | 40 (58.0) | 13 (72.2) | 151 (72.9) |
| Follicular, n (%) | 6 (16.2) | 17 (24.6) | 4 (22.2) | 23 (11.1) |
| Classical/follicular, n (%) | 0 | 3 (4.3) | 0 | 8 (3.9) |
| Oxyphilic, n (%) | 0 | 3 (4.3) | 0 | 6 (2.9) |
| Follicular/oxyphilic, n (%) | 1 (2.7) | 1 (1.4) | 0 | 2 (1.0) |
| Follicular thyroid carcinoma, n (%) | 1 (2.7) | 5 (7.2) | 1 (5.6) | 17 (8.2) |
| Classical, n (%) | 1 (2.7) | 3 (4.3) | 0 | 11 (5.3) |
| Oncocytic (Hürthle Cell) Variant, n (%) | 0 | 2 (2.9) | 1 (5.6) | 6 (2.9) |
| Localization in the right lobe, n (%) | 26 (70.3)a | 33 (47.8)b | 10 (55.6)a,b | 105 (50.7)b |
| Localization in the left lobe, n (%) | 6 (16.2)a | 28 (40.6)b | 6 (33.3)a,b | 85 (41.1)b |
| Localization in both lobes, n (%) | 5 (13.5) | 8 (11.6) | 2 (11.1) | 17 (8.2) |
a,b,c-groups followed by the same letter do not differ statistically significantly