Table 1.
Comparison of GSRS score between HC and D-IBS and between D-IBS (−) and D-IBS (+) patients.
| HC | D-IBS | D-IBS (−) | D-IBS (+) | |
|---|---|---|---|---|
| GSRS single items | ||||
| Epigastric pain | 1 (1–1) | 3.5 (1–7)∗ | 5 (1–7) | 2 (1–6) |
| Gastric hunger pain | 1 (1–1) | 2 (1–7)∗ | 1 (1–7) | 2 (1–5) |
| Abdominal continuous pain | 1 (1–1) | 1 (1–5)∗ | 3 (1–5) | 1 (1–5) |
| Abdominal colic pain | 1 (1–1) | 2 (1–7)∗ | 5 (1–7) | 1 (1–7) |
| Abdominal indefinite pain | 1 (1–1) | 1 (1–5) | 1 (1–5) | 1 (1–3) |
| Nausea | 1 (1–1) | 1 (1–6)∗ | 2 (1–6) | 1 (1–4) |
| Burping | 1 (1–1) | 2 (1–7)∗ | 1 (1–7) | 3 (1–5) |
| Borborygmi | 1 (1–1) | 2 (1–7)∗ | 2 (1–7) | 2 (1–7) |
| Abdominal distension | 1 (1–1) | 5 (1–7)∗ | 5 (1–7) | 5 (1–7) |
| Flatulence | 1 (1–1) | 4.5 (1–7)∗ | 5 (1–7) | 3 (1–6) |
| Postprandial fullness | 1 (1–1) | 3 (1–7)∗ | 4 (1–7) | 3 (1–5) |
| Early satiety | 1 (1–1) | 1 (1–7)∗ | 1 (1–7) | 1 (1–7) |
| Increased passage of stools | 1 (1–1) | 1 (1–7)∗ | 1 (1–3) | 1 (1–7) |
| Soft stool | 1 (1–1) | 1 (1–7)∗ | 3 (1–5) | 1 (1–7) |
| Urgent bowel movement | 1 (1–1) | 1.5 (1–7)∗ | 1 (1–7) | 2 (1–7) |
| Bristol score | 4 (3–4) | 4 (3–7)∗ | 5 (3–6) | 3 (3–7) |
| GSRS cluster scores | ||||
| Pain syndrome | 6 (6–6) | 13 (6–25)∗ | 16 (7–25) | 11 (6–22)∗ |
| Indigestion syndrome | 6 (6–6) | 19 (7–38)∗ | 19 (7–38) | 22 (12–36) |
| Diarrhoea syndrome | 3 (3–3) | 5 (3–21)∗ | 7 (3–15) | 5 (3–21)∗ |
HC: healthy controls; D-IBS (+)/(−): diarrhoea-predominant IBS according to presence/absence of impaired permeability. Data are expressed as median and range and were analysed by rank sum test. ∗(p < 0.05).