Table 1.
HC | D-IBS | D-IBS (−) | D-IBS (+) | |
---|---|---|---|---|
GSRS single items | ||||
Epigastric pain | 1 (1–1) | 3.5 (1–7)∗ | 5 (1–7) | 2 (1–6) |
Gastric hunger pain | 1 (1–1) | 2 (1–7)∗ | 1 (1–7) | 2 (1–5) |
Abdominal continuous pain | 1 (1–1) | 1 (1–5)∗ | 3 (1–5) | 1 (1–5) |
Abdominal colic pain | 1 (1–1) | 2 (1–7)∗ | 5 (1–7) | 1 (1–7) |
Abdominal indefinite pain | 1 (1–1) | 1 (1–5) | 1 (1–5) | 1 (1–3) |
Nausea | 1 (1–1) | 1 (1–6)∗ | 2 (1–6) | 1 (1–4) |
Burping | 1 (1–1) | 2 (1–7)∗ | 1 (1–7) | 3 (1–5) |
Borborygmi | 1 (1–1) | 2 (1–7)∗ | 2 (1–7) | 2 (1–7) |
Abdominal distension | 1 (1–1) | 5 (1–7)∗ | 5 (1–7) | 5 (1–7) |
Flatulence | 1 (1–1) | 4.5 (1–7)∗ | 5 (1–7) | 3 (1–6) |
Postprandial fullness | 1 (1–1) | 3 (1–7)∗ | 4 (1–7) | 3 (1–5) |
Early satiety | 1 (1–1) | 1 (1–7)∗ | 1 (1–7) | 1 (1–7) |
Increased passage of stools | 1 (1–1) | 1 (1–7)∗ | 1 (1–3) | 1 (1–7) |
Soft stool | 1 (1–1) | 1 (1–7)∗ | 3 (1–5) | 1 (1–7) |
Urgent bowel movement | 1 (1–1) | 1.5 (1–7)∗ | 1 (1–7) | 2 (1–7) |
Bristol score | 4 (3–4) | 4 (3–7)∗ | 5 (3–6) | 3 (3–7) |
GSRS cluster scores | ||||
Pain syndrome | 6 (6–6) | 13 (6–25)∗ | 16 (7–25) | 11 (6–22)∗ |
Indigestion syndrome | 6 (6–6) | 19 (7–38)∗ | 19 (7–38) | 22 (12–36) |
Diarrhoea syndrome | 3 (3–3) | 5 (3–21)∗ | 7 (3–15) | 5 (3–21)∗ |
HC: healthy controls; D-IBS (+)/(−): diarrhoea-predominant IBS according to presence/absence of impaired permeability. Data are expressed as median and range and were analysed by rank sum test. ∗(p < 0.05).