Table 1.
Physicochemical properties of nanoparticles
| Nanoparticles | Hydrophobic SPIO NPs | SPIO@DSPE-PEG/DOX NPs | SPIO@DSPE-PEG/DOX/ICG NPs |
|---|---|---|---|
| Size d (nm) | 9.8±0.09 | 20.6±2.10 | 22.9±1.80 |
| Zeta potential (mV) | −38.63±0.10 | −38.52±0.12 | −38.19±0.06 |
| DOX LC (%) | – | 14.45±0.55 | 13.87±0.52 |
| DOX EE (%) | – | 67.45±2.82 | 67.45±2.82 |
| ICG LC (%) | – | – | 4.86±0.14 |
| ICG EE (%) | – | – | 73.48±2.44 |
Note: Data are represented as mean ± SD (n=3).
Abbreviations: DOX, doxorubicin; DSPE-PEG, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)]; EE, encapsulation efficiency; ICG, indocyanine green; LC, loading capacity; SPIO NPs, superparamagnetic iron oxide nanoparticles.