Table 1.

P-values for the two-way analysis of variance of the data.

Parameter	Effect of lithium diet in		Interaction of phenotype with
	Wild type mice	Knockout mice	Control diet	Lithium diet
Water intake	P < 0.001	P = 0.192	P = 0.499	P = 0.036
Urine output	P < 0.001	P = 0.325	P = 0.293	P < 0.001
Urine osmolality	P < 0.001	P = 0.310	P = 0.276	P < 0.001
Urine sodium	P < 0.001	P < 0.001	P = 0.976	P < 0.001
Urine potassium	P < 0.001	P = 0.440	P = 0.669	P < 0.001
AQP2 in medulla	P < 0.001	P = 0.017	P = 0.487	P < 0.001
AQP2 in cortex	P < 0.001	P < 0.001	P < 0.001	P < 0.003
NKCC2 in medulla	P < 0.001	P = 0.166	P = 0.324	P = 0.103
NKCC2 in cortex	P = 0.203	P = 0.001	P = 0.012	P = 0.976
PC in medulla	P < 0.001	P = 0.278	P = 0.447	P = 0.001
PC in cortex	P = 0.025	P = 0.459	P = 0.888	P = 0.006
IC in medulla	P < 0.001	P = 0.316	P = 0.526	P < 0.001
IC in cortex	P < 0.010	P = 0.404	P = 0.880	P = 0.002

PC, principal cells; IC, intercalated cells.