FIGURE 1.
Resveratrol (RES) attenuates SEB-induced liver damage. Mice were untreated (Naïve, Control), treated with RES (100 mg/kg bw) only, SEB+VEH or SEB+RES, as detailed in Section “Materials and Methods.” Livers were harvested, sectioned and H&E staining was performed. (A) A representative of H&E stained livers from the four treatment groups; Naïve group (mice with no treatment: a,b), RES (mice treated with RES only: c,d), SEB+VEH (mice exposed to SEB and treated with VEH: e,f), and SEB+RES (mice exposed to SEB and treated with RES: g,h). (B) Depicts necrotic lesions in the liver of SEB+VEH (e,f) SEB+RES (g,h). (C) Shows total number of MNCs in liver of various treated groups. (D) AST levels in sera. Data presented in (B–D) represent mean ± SEM from groups of five mice. Asterisks (∗) in (B–D) indicate statistically significant (p < 0.05) difference between the groups.