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. 2018 Dec 17;9:2936. doi: 10.3389/fimmu.2018.02936

Figure 3.

Figure 3

Trained Immunity-based Immunostimulants (A) and Adjuvants (B). (A) Immunostimulants: trained immunity (TI) inducers that enhance both nonspecific and adaptive immune responses to eventual bystander pathogens. (B) Adjuvants: trained immunity (TI) inducers that are combined with an antigen. This latter can be co-delivered with the TI-inducers in the same vaccine (AgX), or later on (AgY) in a two-step process, once trained immunity has been achieved.