Table 3.
Brain regions showing significantly altered RSFC of PUT in RLS.
| Seed regions | Cluster size | Peak MNI coordinates | Peak intensity | Brain regions | Cohen's f2 |
|---|---|---|---|---|---|
| PUT.R | 184 | (0, 30, 18) | −6.021 | CG | 1.066 |
| drPUT.L | 71 | (−30, 0, 9) | −5.300 | PUT.L | 0.826 |
| 83 | (33, 3, 9) | −6.939 | PUT.R | 1.416 | |
| 43 | (−9, 30, 18) | −5.267 | CG.L | 0.816 | |
| dcPUT.L | 37 | (−24, 18, −3) | −5.509 | PUT.L | 0.893 |
| 38 | (−27, 51, 24) | −4.942 | FP.L | 0.718 | |
| 52 | (3, 12, 69) | −4.957 | SFG.R | 0.723 | |
| vrPUT.L | 219 | (24, 15, −6) | −6.443 | PUT.R | 1.221 |
| 196 | (−27, 6, −3) | −6.540 | PUT.L | 1.258 | |
| 32 | (−30, 48, 9) | −4.618 | FP.L | 0.627 | |
| 56 | (−36, 3, 27) | −5.606 | PreCG.L | 0.924 | |
| 122 | (6, 30, 33) | −4.962 | ParaCG.R | 0.724 | |
| drPUT.R | 54 | (12, −51, −33) | 6.040 | CERE.R | 1.073 |
| 104 | (−18, 12, 3) | −5.768 | PUT.L | 0.979 | |
| 60 | (12, 12, 3) | −5.378 | CAU.R | 0.851 | |
| 73 | (−30, 48, 24) | −5.565 | FP.L | 0.911 | |
| 61 | (6, 30, 39) | −5.085 | ParaCG.R | 0.761 | |
| dcPUT.R | 83 | (−21, 12, 3) | −5.288 | PUT.L | 0.822 |
| vrPUT.R | 44 | (−12, 12, −3) | −5.444 | CAU.L | 0.871 |
| 60 | (27, 12, −3) | −5.040 | PUT.R | 0.747 | |
| 97 | (−3, 33, 45) | −5.987 | SCG.L | 1.054 |
The significance was determined using Gaussian random field (GRF) correction, voxel level p < 0.001, cluster level p < 0.05. MNI, Montreal Neurological Institute; CG, cingulate gyrus; FP, frontal pole; SFG, superior frontal gyrus; CAU, caudate; PreCG, precentral gyrus; ParaCG, paracingulate gyrus; and CERE, cerebellum.