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. 2018 Dec 17;12:112. doi: 10.3389/fncir.2018.00112

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Copyright © 2018 Saito, Sawada and Aoki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Typical images of manganese-enhanced MRI (MEMRI). Top panel: MEMRI of normal rat whole brain (A–C; horizontal slice) and hippocampus (D; axial slice). Bottom panel: MEMRI of a radiation-exposed rat (E–G; horizontal slice) and hippocampus (H; axial slice). White arrows indicate ventricle dilatation in (E–H). T₁ enhancement is seen around the whole hippocampal area of normal rat brain; however, T₁ enhancement was different between normal and radiation-exposed rat brains, especially in dentate gyrus (DG) and CA3. Cb, cerebellum; Hf, hippocampal formation (red arrow head); Ob, olfactory bulb.