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Effects of SKSF on the mRNA expression of miR-21. Data are expressed as mean ± SD, n =10 rats per group. (N) Normal group, (M) model group, (Met) metformin group, (SKSFh) Spleen-Kidney Supplementing Formula group at a high dose, (SKSFm) Spleen-Kidney Supplementing Formula group at a medium dose, (SKSFl) Spleen-Kidney Supplementing Formula group at a low dose. ∗P < 0.05, ∗∗P <0.01 compared with model group.
