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. 2018 Dec 17;9:1796. doi: 10.3389/fphys.2018.01796

FIGURE 6.

FIGURE 6

Phosphorylation levels of signaling proteins involved in regulation of mitochondrial adaptations for CON, BFRRE, and HLRE groups. (A) representative immunoblots for all proteins at all conditions. (B) phosphorylated 5′ AMP-activated protein kinase (p-AMPK). (C) phosphorylated acetyl-CoA carboxylase (p-ACC). (D) phosphorylated p38 mitogen-activated protein kinase (p-p38 MAPK). (E) phosphorylated calcium/calmodulin-dependent protein kinase II (p-CaMKII). (F) phosphorylated cAMP response-element binding protein (p-CREB). (G) phosphorylated p53 (p-p53). ∗ denotes difference from pre-values within groups (P < 0.05), ∗∗ denotes difference from pre-values within groups (P < 0.01), C denotes difference from CON at corresponding time point (P < 0.05), CC denotes difference from CON at corresponding time point (P < 0.01). Data are presented as mean fold changes ± SD. Overall effects are designated in the upper left corner of each graph.