Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 4;9(1):2045894018820813. doi: 10.1177/2045894018820813

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Fig. 2. — Schistosoma-exposed mice have a significantly lower Th-2 immune response and no significant difference in Th-1 and Th-17 immune response when treated with paclitaxel. (a) IL-4, IL-13, and INF-γ protein concentrations in paclitaxel-treated and vehicle treated mice; t-test. (b) Estimated granuloma volumes; t-test. (c) Flow sorting of CD4⁺ and Th2 CD4⁺ (intracellular IL-4⁺) T cells (representative of n = 3 per group). (d) Percentage of all cells which are Th-1 (IFN-γ⁺), Th-2 (IL-4⁺), and Th-17 (IL-17A⁺ or IL-17F⁺) T cells; n = 3 per group; t-test. (e) IL-23 mRNA expression (as a marker of Th-17 inflammation); t-test. (f) Residual intrapulmonary Schistosoma egg burden in paclitaxel-treated and vehicle-treated mice; t-test. Graphs show mean ± SD.