Table 5.
Best response | |||||||
---|---|---|---|---|---|---|---|
Overall | P value∗ | Pancreatic | GI | ||||
PD (%) | SD + PR (%) | PD (%) | SD + PR (%) | PD (%) | SD + PR (%) | ||
Overall | 3 (33.3) | 6 (66.7) | 1 (33.3) | 2 (66.7) | 2 (33.3) | 4 (66.7) | |
ATRX + DAXX | |||||||
Negative | 0 (0.0) | 3 (50.0) | 0.464 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 3 (75.0) |
Positive | 3 (100.0) | 3 (50.0) | 1 (100.0) | 2 (100.0) | 2 (100.0) | 1 (25.0) | |
RB1 | |||||||
Negative | 1 (33.3) | 4 (66.7) | 0.524 | 0 (0.0) | 1 (50.0) | 1 (50.0) | 3 (75.0) |
Positive | 2 (66.7) | 2 (33.3) | 1 (100.0) | 1 (50.0) | 1 (50.0) | 1 (25.0) |
PD: progressive disease; SD: stable disease; PR: partial response; GI: gastrointestinal. ∗P-value was calculated on the overall number of patients.