(c) Association between SP110 SNP genotypes and TB risk in TB patients vs. healthy controls
| SNP ID | Genotypes | Health no. (%) | LTBI no. (%) | OR (95% CI) | p value |
|---|---|---|---|---|---|
| rs7580912 | AA | 134 (49) | 129 (43) | Ref | — |
| GA | 111 (41) | 139 (47) | 1.258 (0.869-1.822) | 0.224 | |
| GG | 27 (10) | 31 (10) | 0.877 (0.474-1.622) | 0.676 | |
| rs7580900 | AA | 100 (37) | 98 (33) | Ref | — |
| GA | 128 (47) | 151 (50) | 1.258 (0.851-1.86) | 0.249 | |
| GG | 43 (16) | 50 (17) | 1.023 (0.601-1.74) | 0.934 | |
| rs11556887 | CC | 206 (76) | 248 (83) | Ref | — |
| CT | 64 (23.6) | 47 (16) | 0.626 (0.401-0.976) | 0.039 | |
| TT | 1 (0.4) | 4 (1) | 2.387 (0.243-23.458) | 0.456 | |
| rs9061 | GG | 176 (65) | 203 (68) | Ref | — |
| AA | 17 (6) | 15 (5) | 0.792 (0.36-1.742) | 0.561 | |
| GA | 79 (29) | 79 (27) | 0.886 (0.597-1.313) | 0.546 | |
| rs3820974 | CC | 125 (46) | 136 (45) | Ref | — |
| AA | 29 (11) | 32 (11) | 0.871 (0.473-1.603) | 0.657 | |
| CA | 118 (43) | 131 (44) | 0.942 (0.651-1.363) | 0.749 | |
| rs1365776 | AA | 217 (81) | 240 (80) | Ref | — |
| GA | 47 (18) | 51 (17) | 0.931 (0.582-1.489) | 0.767 | |
| GG | 4 (2) | 8 (3) | 2.291 (0.631-8.322) | 0.208 | |
| rs41309108 | TT | 153 (56) | 176 (59) | Ref | — |
| AA | 9 (3) | 12 (4) | 0.982 (0.382-2.527) | 0.971 | |
| TA | 109 (40) | 111 (37) | 0.852 (0.593-1.225) | 0.387 | |
| rs2241525 | GG | 186 (69) | 211 (71) | Ref | — |
| AA | 10 (3) | 12 (4) | 1.004 (0.402-2.505) | 0.994 | |
| GA | 75 (28) | 73 (25) | 0.85 (0.569-1.268) | 0.425 | |
| rs1135791 | TT | 206 (75) | 212 (71) | Ref | — |
| CC | 3 (1) | 5 (2) | 1.681 (0.371-7.617) | 0.5 | |
| CT | 64 (24) | 82 (27) | 1.177 (0.788-1.76) | 0.426 | |
| rs10498244 | AA | 199 (75) | 215 (72) | Ref | — |
| AG | 61 (23) | 80 (27) | 1.185 (0.787-1.785) | 0.417 | |
| GG | 5 (2) | 4 (1) | 0.774 (0.191-3.133) | 0.719 |
OR: odds ratio; CI: confidence interval; ORs are adjusted for gender. The significant ORs are shown in italic.