(c) Association analyses of SP110 SNP genotypes in a recessive model
| SNP ID | TB vs. health | TB vs. LTBI | LTBI vs. health | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
| rs9061 | 0.82 (0.38,1.78) | 0.6227 | — | — | — | — |
| rs7580900 | 0.92 (0.57,1.48) | 0.737 | 0.45 (0.24,0.84) | 0.0117 | 2.13 (1.13,4.03) | 0.0195 ∗ |
| rs3820974 | 0.92 (0.52,1.62) | 0.7796 | 1.13 (0.45,2.83) | 0.8018 | 0.84 (0.33,2.15) | 0.7209 |
| rs41309108 | 1.05 (0.41,2.66) | 0.9241 | 2.35 (0.3,18.52) | 0.4186 | 0.43 (0.05,3.55) | 0.437 |
| rs7580912 | 0.79 (0.44,1.42) | 0.4367 | 0.35 (0.17,0.72) | 0.0043 | 2.49 (1.2,5.18) | 0.0142 ∗ |
| rs1135791 | 1.63 (0.36,7.51) | 0.5284 | — | — | — | — |
| rs1365776 | 2.25 (0.63,8.05) | 0.2129 | 1.94 (0.23,16.11) | 0.5375 | 1.24 (0.13,11.51) | 0.8504 |
| rs10498244 | 0.74 (0.18,3.05) | 0.6804 | 0.38 (0.06,2.23) | 0.2844 | 2.27 (0.42,12.19) | 0.3385 |
| rs2241525 | 1.05 (0.42,2.6) | 0.9172 | 0.56 (0.17,1.83) | 0.3374 | 1.73 (0.52,5.81) | 0.3747 |
| rs11556887 | 2.63 (0.27,25.7) | 0.4064 | — | — | — | — |
OR: odds ratio; CI: confidence interval; ORs are adjusted for gender. The significant ORs are shown in italic. ∗ORs remain significant after false discovery rate (FDR) correction.